Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity

Broad antibody sensitivity differences of hepatitis C virus (HCV) isolates and their ability to persist in the presence of neutralizing antibodies (NAbs) remain poorly understood. Here, we show that polymorphisms within glycoprotein E2, including hypervariable region 1 (HVR1) and antigenic site 412...

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Detalles Bibliográficos
Autores principales: Augestad, Elias H., Castelli, Matteo, Clementi, Nicola, Ströh, Luisa J., Krey, Thomas, Burioni, Roberto, Mancini, Nicasio, Bukh, Jens, Prentoe, Jannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449684/
https://www.ncbi.nlm.nih.gov/pubmed/32923643
http://dx.doi.org/10.1126/sciadv.abb5938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449684/
https://www.ncbi.nlm.nih.gov/pubmed/32923643
http://dx.doi.org/10.1126/sciadv.abb5938

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