Fate mapping via CCR2-CreER mice reveals monocyte-to-microglia transition in development and neonatal stroke

Whether monocytes contribute to the brain microglial pool in development or after brain injury remains contentious. To address this issue, we generated CCR2-CreER mice to track monocyte derivatives in a tamoxifen-inducible manner. This method labeled Ly6C(hi) and Ly6C(lo) monocytes after tamoxifen d...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hong-Ru, Sun, Yu-Yo, Chen, Ching-Wen, Kuo, Yi-Min, Kuan, Irena S., Tiger Li, Zheng-Rong, Short-Miller, Jonah C., Smucker, Marchelle R., Kuan, Chia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449686/
https://www.ncbi.nlm.nih.gov/pubmed/32923636
http://dx.doi.org/10.1126/sciadv.abb2119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449686/
https://www.ncbi.nlm.nih.gov/pubmed/32923636
http://dx.doi.org/10.1126/sciadv.abb2119

Ejemplares similares