Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian randomisation

We examined whether specifically statins, of the major lipid modifiers (statins, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and ezetimibe) have pleiotropic effects on ischemic heart disease (IHD) via testosterone in men or women. As a validation, we similarly assessed whether a...

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Detalles Bibliográficos
Autores principales: Schooling, CM, Zhao, JV, Au Yeung, SL, Leung, GM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449694/
https://www.ncbi.nlm.nih.gov/pubmed/32838838
http://dx.doi.org/10.7554/eLife.58567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449694/
https://www.ncbi.nlm.nih.gov/pubmed/32838838
http://dx.doi.org/10.7554/eLife.58567

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