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Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian randomisation
We examined whether specifically statins, of the major lipid modifiers (statins, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and ezetimibe) have pleiotropic effects on ischemic heart disease (IHD) via testosterone in men or women. As a validation, we similarly assessed whether a...
Autores principales: | Schooling, CM, Zhao, JV, Au Yeung, SL, Leung, GM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449694/ https://www.ncbi.nlm.nih.gov/pubmed/32838838 http://dx.doi.org/10.7554/eLife.58567 |
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