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The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription

Compared to other stages in the RNA polymerase II transcription cycle, the role of chromatin in transcription termination is poorly understood. We performed a genetic screen in Saccharomyces cerevisiae to identify histone mutants that exhibit transcriptional readthrough of terminators. Amino acid su...

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Detalles Bibliográficos
Autores principales: Hildreth, A Elizabeth, Ellison, Mitchell A, Francette, Alex M, Seraly, Julia M, Lotka, Lauren M, Arndt, Karen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449698/
https://www.ncbi.nlm.nih.gov/pubmed/32845241
http://dx.doi.org/10.7554/eLife.57757