Cargando…

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription

Compared to other stages in the RNA polymerase II transcription cycle, the role of chromatin in transcription termination is poorly understood. We performed a genetic screen in Saccharomyces cerevisiae to identify histone mutants that exhibit transcriptional readthrough of terminators. Amino acid su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hildreth, A Elizabeth, Ellison, Mitchell A, Francette, Alex M, Seraly, Julia M, Lotka, Lauren M, Arndt, Karen M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449698/ https://www.ncbi.nlm.nih.gov/pubmed/32845241 http://dx.doi.org/10.7554/eLife.57757

Ejemplares similares

Pervasive transcription fine-tunes replication origin activity
por: Candelli, Tito, et al.
Publicado: (2018)

A transcriptional switch controls meiosis
por: Hildreth, A Elizabeth, et al.
Publicado: (2017)

Independent manipulation of histone H3 modifications in individual nucleosomes reveals the contributions of sister histones to transcription
por: Zhou, Zhen, et al.
Publicado: (2017)

Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma
por: Grosso, Ana R, et al.
Publicado: (2015)

Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance
por: du Mee, Dorine Jeanne Mariëtte, et al.
Publicado: (2018)

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription
por: Di Cerbo, Vincenzo, et al.
Publicado: (2014)

An asymmetric centromeric nucleosome
por: Ichikawa, Yuichi, et al.
Publicado: (2018)

Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA
por: Parker, Matthew T, et al.
Publicado: (2021)

Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome
por: Armache, Jean Paul, et al.
Publicado: (2019)

Transcriptional adaptation in Caenorhabditis elegans
por: Serobyan, Vahan, et al.
Publicado: (2020)

A synthetic biology approach to probing nucleosome symmetry
por: Ichikawa, Yuichi, et al.
Publicado: (2017)

Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm
por: Yang, Xinan H, et al.
Publicado: (2017)

Nup98-dependent transcriptional memory is established independently of transcription
por: Pascual-Garcia, Pau, et al.
Publicado: (2022)

Genetic dissection of the RNA polymerase II transcription cycle
por: Chou, Shao-Pei, et al.
Publicado: (2022)

Synthetic analysis of chromatin tracing and live-cell imaging indicates pervasive spatial coupling between genes
por: Bohrer, Christopher H, et al.
Publicado: (2023)

Effective dynamics of nucleosome configurations at the yeast PHO5 promoter
por: Wolff, Michael Roland, et al.
Publicado: (2021)

Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation
por: Henikoff, Steven, et al.
Publicado: (2020)

Transcription elongation is finely tuned by dozens of regulatory factors
por: Couvillion, Mary, et al.
Publicado: (2022)

Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor
por: Xu, Juncao, et al.
Publicado: (2019)

Ion counting demonstrates a high electrostatic field generated by the nucleosome
por: Gebala, Magdalena, et al.
Publicado: (2019)

Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome
por: Worden, Evan J, et al.
Publicado: (2020)

Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops
por: Sabino, João C, et al.
Publicado: (2022)

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome
por: Sundaramoorthy, Ramasubramanian, et al.
Publicado: (2018)

Simultaneous measurement of chromatin accessibility, DNA methylation, and nucleosome phasing in single cells
por: Pott, Sebastian
Publicado: (2017)

CTCF confers local nucleosome resiliency after DNA replication and during mitosis
por: Owens, Nick, et al.
Publicado: (2019)

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
por: Bacic, Luka, et al.
Publicado: (2021)

Heterochromatin-dependent transcription of satellite DNAs in the Drosophila melanogaster female germline
por: Wei, Xiaolu, et al.
Publicado: (2021)

The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome
por: Morrison, Emma A, et al.
Publicado: (2018)

The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h
por: Gamarra, Nathan, et al.
Publicado: (2018)

The tardigrade damage suppressor protein binds to nucleosomes and protects DNA from hydroxyl radicals
por: Chavez, Carolina, et al.
Publicado: (2019)

Universally high transcript error rates in bacteria
por: Li, Weiyi, et al.
Publicado: (2020)

Nucleotide-level linkage of transcriptional elongation and polyadenylation
por: Geisberg, Joseph V, et al.
Publicado: (2022)

Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs
por: Shen, Zeyang, et al.
Publicado: (2022)

Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
por: Friman, Elias T, et al.
Publicado: (2019)

Asymmetry between the two acidic patches dictates the direction of nucleosome sliding by the ISWI chromatin remodeler
por: Levendosky, Robert F, et al.
Publicado: (2019)

Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos
por: Mir, Mustafa, et al.
Publicado: (2018)

Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants
por: White, Richard J, et al.
Publicado: (2022)

Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency
por: Greenberg, Maxim, et al.
Publicado: (2019)

Transcription factor clusters regulate genes in eukaryotic cells
por: Wollman, Adam JM, et al.
Publicado: (2017)

Multi-enhancer transcriptional hubs confer phenotypic robustness
por: Tsai, Albert, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rsn2hh7e8lj34sllteceo1er4u