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Proportions of B-cell subsets are altered in incomplete systemic lupus erythematosus and correlate with interferon score and IgG levels

OBJECTIVES: Incomplete SLE (iSLE) patients display symptoms typical for SLE but have insufficient criteria to fulfil the diagnosis. Biomarkers are needed to identify iSLE patients that will progress to SLE. IFN type I activation, B-cell-activating factor (BAFF) and B-cell subset distortions play an...

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Detalles Bibliográficos
Autores principales: Henning, Svenja, Lambers, Wietske M, Doornbos-van der Meer, Berber, Abdulahad, Wayel H, Kroese, Frans G M, Bootsma, Hendrika, Westra, Johanna, de Leeuw, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449809/
https://www.ncbi.nlm.nih.gov/pubmed/32259240
http://dx.doi.org/10.1093/rheumatology/keaa114