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Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension

Rationale: Hypertension is a major risk factor for cerebral small vessel disease, the most prevalent cause of vascular cognitive impairment. As we have shown, hypertension induced by a prolonged Angiotensin II infusion is associated with increased permeability of the blood-brain barrier (BBB), chron...

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Detalles Bibliográficos
Autores principales: Kerkhofs, Danielle, van Hagen, Britt T., Milanova, Irina V., Schell, Kimberly J., van Essen, Helma, Wijnands, Erwin, Goossens, Pieter, Blankesteijn, W. Matthijs, Unger, Thomas, Prickaerts, Jos, Biessen, Erik A., van Oostenbrugge, Robert J., Foulquier, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449902/
https://www.ncbi.nlm.nih.gov/pubmed/32863942
http://dx.doi.org/10.7150/thno.44394