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Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension
Rationale: Hypertension is a major risk factor for cerebral small vessel disease, the most prevalent cause of vascular cognitive impairment. As we have shown, hypertension induced by a prolonged Angiotensin II infusion is associated with increased permeability of the blood-brain barrier (BBB), chron...
Autores principales: | Kerkhofs, Danielle, van Hagen, Britt T., Milanova, Irina V., Schell, Kimberly J., van Essen, Helma, Wijnands, Erwin, Goossens, Pieter, Blankesteijn, W. Matthijs, Unger, Thomas, Prickaerts, Jos, Biessen, Erik A., van Oostenbrugge, Robert J., Foulquier, Sébastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449902/ https://www.ncbi.nlm.nih.gov/pubmed/32863942 http://dx.doi.org/10.7150/thno.44394 |
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