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DNA methylation downregulated ZDHHC1 suppresses tumor growth by altering cellular metabolism and inducing oxidative/ER stress-mediated apoptosis and pyroptosis

Cancer progression is an intricate biological process profiled by not only unscheduled proliferation, but also altered metabolism mechanisms. In this article, we introduced a novel tumor suppressor gene (TSG), Zinc Finger DHHC-Type Containing 1 (ZDHHC1, also known as ZNF377), frequently silenced due...

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Detalles Bibliográficos
Autores principales: Le, Xin, Mu, Junhao, Peng, Weiyan, Tang, Jun, Xiang, Qin, Tian, Shaorong, Feng, Yixiao, He, Sanxiu, Qiu, Zhu, Ren, Guosheng, Huang, Ailong, Lin, Yong, Tao, Qian, Xiang, Tingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449911/
https://www.ncbi.nlm.nih.gov/pubmed/32863941
http://dx.doi.org/10.7150/thno.45631