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Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell lines

Rationale: Gastric cancer (GC) is a solid tumor that contains subpopulations of cancer stem cells (CSCs), which are considered drivers of tumor initiation and metastasis; responsible for therapeutic resistance; and promoters of tumor relapse. The balance between symmetric and asymmetric division is...

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Detalles Bibliográficos
Autores principales: Pajuelo-Lozano, Natalia, Alcalá, Sonia, Sainz, Bruno, Perona, Rosario, Sanchez-Perez, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449921/
https://www.ncbi.nlm.nih.gov/pubmed/32863948
http://dx.doi.org/10.7150/thno.49270