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Loss of SIRT4 promotes the self-renewal of Breast Cancer Stem Cells

Rationale: It has been proposed that cancer stem/progenitor cells (or tumor-initiating cells, TICs) account for breast cancer initiation and progression. Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent class-III histone deacetylases and mediate various basic biological processes, inc...

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Detalles Bibliográficos
Autores principales: Du, Lutao, Liu, Xiaoyan, Ren, Yidan, Li, Juan, Li, Peilong, Jiao, Qinlian, Meng, Peng, Wang, Fang, Wang, Yuli, Wang, Yun-shan, Wang, Chuanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449925/
https://www.ncbi.nlm.nih.gov/pubmed/32863939
http://dx.doi.org/10.7150/thno.44688