Assessment of DNA damage by 53PB1 and pKu70 detection in peripheral blood lymphocytes by immunofluorescence and high-resolution transmission electron microscopy

PURPOSE: 53BP1 foci detection in peripheral blood lymphocytes (PBLs) by immunofluorescence microscopy (IFM) is a sensitive and quantifiable DNA double-strand break (DSB) marker. In addition, high-resolution transmission electron microscopy (TEM) with immunogold labeling of 53BP1 and DSB-bound phosph...

Descripción completa

Detalles Bibliográficos
Autores principales: Lorat, Yvonne, Fleckenstein, Jochen, Görlinger, Patric, Rübe, Christian, Rübe, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449954/
https://www.ncbi.nlm.nih.gov/pubmed/32006067
http://dx.doi.org/10.1007/s00066-020-01576-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449954/
https://www.ncbi.nlm.nih.gov/pubmed/32006067
http://dx.doi.org/10.1007/s00066-020-01576-1

Ejemplares similares