Cargando…

Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2

In view of recent global pandemic the 3-alkynyl substituted 2-chloroquinoxaline framework has been explored as a potential template for the design of molecules targeting COVID-19. Initial in silico studies of representative compounds to assess their binding affinities via docking into the N-terminal...

Descripción completa

Detalles Bibliográficos
Autores principales: Shahinshavali, Shaik, Hossain, Kazi Amirul, Kumar, Abbaraju Venkata Durga Nagendra, Reddy, Alugubelli Gopi, Kolli, Deepti, Nakhi, Ali, Rao, Mandava Venkata Basaveswara, Pal, Manojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449981/
https://www.ncbi.nlm.nih.gov/pubmed/32868957
http://dx.doi.org/10.1016/j.tetlet.2020.152336