Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans

Although traditional egg-based inactivated influenza vaccines can protect against infection, there have been significant efforts to develop improved formats to overcome disadvantages of this platform. Here, we have assessed human CD4 T cell responses to a traditional egg-based influenza vaccine with...

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Detalles Bibliográficos
Autores principales: Richards, K. A., Moritzky, S., Shannon, I., Fitzgerald, T., Yang, H., Branche, A., Topham, D. J., Treanor, J. J., Nayak, J., Sant, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450042/
https://www.ncbi.nlm.nih.gov/pubmed/32884842
http://dx.doi.org/10.1038/s41541-020-00227-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450042/
https://www.ncbi.nlm.nih.gov/pubmed/32884842
http://dx.doi.org/10.1038/s41541-020-00227-x

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