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Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness

Recent findings show that MRP4 is critical for pancreatic ductal adenocarcinoma (PDAC) cell proliferation. Nevertheless, the significance of MRP4 protein levels and function in PDAC progression is still unclear. The aim of this study was to determine the role of MRP4 in PDAC tumor aggressiveness. Bi...

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Detalles Bibliográficos
Autores principales: Sahores, A., Carozzo, A., May, M., Gómez, N., Di Siervi, N., De Sousa Serro, M., Yaneff, A., Rodríguez-González, A., Abba, M., Shayo, C., Davio, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450045/
https://www.ncbi.nlm.nih.gov/pubmed/32848164
http://dx.doi.org/10.1038/s41598-020-71181-w