Post-translational modification as a response to cellular stress induced by hemoglobin oxidation in sickle cell disease

Intracellular oxidative stress and oxidative modification of sickle hemoglobin (HbS) play a role in sickle cell disease (SCD) pathogenesis. Recently, we reported that Hb-dependent oxidative stress induced post-translational modifications (PTMs) of Hb and red blood cell (RBC) membrane proteins of tra...

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Detalles Bibliográficos
Autores principales: Strader, Michael Brad, Jana, Sirsendu, Meng, Fantao, Heaven, Michael R., Shet, Arun S., Thein, Swee Lay, Alayash, Abdu I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450072/
https://www.ncbi.nlm.nih.gov/pubmed/32848178
http://dx.doi.org/10.1038/s41598-020-71096-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450072/
https://www.ncbi.nlm.nih.gov/pubmed/32848178
http://dx.doi.org/10.1038/s41598-020-71096-6

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