The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation

Oncoprotein E6 of high-risk human papillomavirus (HPV) plays a critical role in inducing cell immortalization and malignancy. E6 downregulates caspase-dependent pathway through the degradation of p53. However, the effect of HPV E6 on other pathways is still under investigation. In the present study,...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimada, Masaru, Yamashita, Akio, Saito, Manami, Ichino, Motohide, Kinjo, Takao, Mizuki, Nobuhisa, Klinman, Dennis M., Okuda, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450093/
https://www.ncbi.nlm.nih.gov/pubmed/32848167
http://dx.doi.org/10.1038/s41598-020-71134-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450093/
https://www.ncbi.nlm.nih.gov/pubmed/32848167
http://dx.doi.org/10.1038/s41598-020-71134-3

Ejemplares similares