Cargando…

T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4

T cell-mediated immunity is governed primarily by T cell receptor (TCR) recognition of peptide-human leukocyte antigen (pHLA) complexes and is essential for immunosurveillance and disease control. This interaction is generally stabilized by interactions between the HLA surface and TCR germline-encod...

Descripción completa

Detalles Bibliográficos
Autores principales: Coles, Charlotte H., McMurran, Catriona, Lloyd, Angharad, Hock, Miriam, Hibbert, Linda, Raman, Marine C. C., Hayes, Conor, Lupardus, Patrick, Cole, David K., Harper, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450119/
https://www.ncbi.nlm.nih.gov/pubmed/32532817
http://dx.doi.org/10.1074/jbc.RA120.014016