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Garcinoic acid prevents β-amyloid (Aβ) deposition in the mouse brain

Garcinoic acid (GA or δ-T3-13'COOH), is a natural vitamin E metabolite that has preliminarily been identified as a modulator of nuclear receptors involved in β-amyloid (Aβ) metabolism and progression of Alzheimer's disease (AD). In this study, we investigated GA's effects on Aβ oligom...

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Detalles Bibliográficos
Autores principales: Marinelli, Rita, Torquato, Pierangelo, Bartolini, Desirée, Mas-Bargues, Cristina, Bellezza, Guido, Gioiello, Antimo, Borras, Consuelo, De Luca, Antonella, Fallarino, Francesca, Sebastiani, Bartolomeo, Mani, Sridhar, Sidoni, Angelo, Viña, Jose, Leri, Manuela, Bucciantini, Monica, Nardiello, Pamela, Casamenti, Fiorella, Galli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450134/
https://www.ncbi.nlm.nih.gov/pubmed/32616652
http://dx.doi.org/10.1074/jbc.RA120.013303