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Tbet promotes CXCR6 expression in immature natural killer cells and natural killer cell egress from the bone marrow

Tbet‐deficient mice have reduced natural killer (NK) cells in blood and spleen, but increased NK cells in bone marrow and lymph nodes, a phenotype that is thought to be the result of defective migration. Here, we revisit the role of Tbet in NK cell bone marrow egress. We definitively show that the a...

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Detalles Bibliográficos
Autores principales: Cuff, Antonia O., Perchet, Thibaut, Dertschnig, Simone, Golub, Rachel, Male, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450165/
https://www.ncbi.nlm.nih.gov/pubmed/32383173
http://dx.doi.org/10.1111/imm.13204