Formulation and Characterization of Cinnarizine Targeted Aural Transfersomal Gel for Vertigo Treatment: A Pharmacokinetic Study on Rabbits

INTRODUCTION AND AIM: Cinnarizine is indicated orally for treating vertigo associated with Ménière’s syndrome and has a local anesthetic effect as well. The present study aims to develop an aural Cinnarizine mucoadhesive transfersomal gel to overcome the first-pass metabolism. METHODS: Eighteen Cinn...

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Detalles Bibliográficos
Autores principales: Abdelmonem, Rehab, Hamed, Raghda Rabe, Abdelhalim, Sally A, ElMiligi, Mohamed F, El-Nabarawi, Mohamed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450212/
https://www.ncbi.nlm.nih.gov/pubmed/32904111
http://dx.doi.org/10.2147/IJN.S258764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450212/
https://www.ncbi.nlm.nih.gov/pubmed/32904111
http://dx.doi.org/10.2147/IJN.S258764

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