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Total Synthesis of (+)-Raputindole A: An Iridium-Catalyzed Cyclization Approach
[Image: see text] This work describes the total synthesis of raputindole A (1) through a convergent approach that features (1) an iridium-catalyzed cyclization to assemble the tricyclic core of the northern part, (2) enzymatic resolution to secure the preparation of an enantiomerically pure benzylic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450706/ https://www.ncbi.nlm.nih.gov/pubmed/32806179 http://dx.doi.org/10.1021/acs.orglett.0c01943 |