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Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain

Alzheimer’s disease (AD) neuropathologic change is characterized by amyloid plaques and neurofibrillary tangles (NFTs) that consist of aggregated amyloid beta (Abeta) and hyperphosphorylated tau proteins (p-tau), respectively. Although the global relationship between Abeta and p-tau has been studied...

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Detalles Bibliográficos
Autores principales: Horie, Kanta, Barthélemy, Nicolas R., Mallipeddi, Nipun, Li, Yan, Franklin, Erin E., Perrin, Richard J., Bateman, Randall J., Sato, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450927/
https://www.ncbi.nlm.nih.gov/pubmed/32854776
http://dx.doi.org/10.1186/s40478-020-01019-z