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Total Number of Alterations in Liquid Biopsies Is an Independent Predictor of Survival in Patients With Advanced Cancers

PURPOSE: Studies have demonstrated an association between quantity of circulating tumor DNA (ctDNA) and poorer survival. We investigated the relationship between percent ctDNA (%ctDNA), total number of ctDNA alterations, and overall survival (OS) in liquid biopsies. MATERIALS AND METHODS: Overall, 4...

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Detalles Bibliográficos
Autores principales: Vu, Peter, Khagi, Yulian, Riviere, Paul, Goodman, Aaron, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450932/
https://www.ncbi.nlm.nih.gov/pubmed/32923910
http://dx.doi.org/10.1200/PO.19.00204