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Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of middle-aged to old individuals. The pathophysiological process of AD is believed to begin many years before the emergence of clinical symptoms. The important influence of congenital genetic aberrations on the develop...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Wang, Yifan, Liu, Yinghua, Dai, Chun-Ling, Tung, Yunn-Chyn, Liu, Fei, Iqbal, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450938/
https://www.ncbi.nlm.nih.gov/pubmed/32854771
http://dx.doi.org/10.1186/s13195-020-00666-7