Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides

BACKGROUND: Approximately 40% of prescribed drugs exert their activity via GTP-binding protein-coupled receptors (GPCRs). Once activated, these receptors cause transient changes in the concentration of second messengers, e.g., cyclic adenosine 3′,5′-monophosphate (cAMP). Specific and efficacious gen...

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Detalles Bibliográficos
Autores principales: Gruteser, Nadine, Kohlhas, Viktoria, Balfanz, Sabine, Franzen, Arne, Günther, Anne, Offenhäusser, Andreas, Müller, Frank, Nikolaev, Viacheslav, Lohse, Martin J., Baumann, Arnd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450941/
https://www.ncbi.nlm.nih.gov/pubmed/32854679
http://dx.doi.org/10.1186/s12896-020-00633-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450941/
https://www.ncbi.nlm.nih.gov/pubmed/32854679
http://dx.doi.org/10.1186/s12896-020-00633-y

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