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Giant cell tumor stromal cells: osteoblast lineage-derived cells secrete IL-6 and IL-10 for M2 macrophages polarization

BACKGROUND: The giant cell tumor (GCT) is a benign tumor which consists of three types cells: mononuclear histiocytic cells (MNHCs), multinuclear giant cells (MNGCs), and GCT stromal cells (GCTSCs). Numerous studies claim that GCTSCs have mesenchymal stem cells (MSCs) characters and play an importan...

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Detalles Bibliográficos
Autores principales: Yang, Kuan, Bao, Lihui, He, Xiaoning, Zhao, Wanmin, Fei, Dongdong, Li, Bei, Xue, Yang, Dong, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450992/
https://www.ncbi.nlm.nih.gov/pubmed/32904108
http://dx.doi.org/10.7717/peerj.9748