Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model

BACKGROUND & AIMS: Infection with hepatitis C virus (HCV) remains a major cause of morbidity and mortality worldwide despite the recent advent of highly effective direct-acting antivirals. The envelope glycoproteins of HCV are heavily glycosylated with a high proportion of high-mannose glycans (...

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Detalles Bibliográficos
Autores principales: Dent, Matthew, Hamorsky, Krystal, Vausselin, Thibaut, Dubuisson, Jean, Miyata, Yoshinari, Morikawa, Yoshio, Matoba, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451001/
https://www.ncbi.nlm.nih.gov/pubmed/32861832
http://dx.doi.org/10.1016/j.jcmgh.2020.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451001/
https://www.ncbi.nlm.nih.gov/pubmed/32861832
http://dx.doi.org/10.1016/j.jcmgh.2020.08.009

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