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Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes

Antibodies have the ability to bind various types of antigens and to recognize different antibody-binding sites (epitopes) of the same antigen with different binding affinities. Due to the conserved structural framework of antibodies, their specificity to antigens is mainly determined by their antig...

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Detalles Bibliográficos
Autores principales: Fernández-Quintero, Monica L, Loeffler, Johannes R, Waibl, Franz, Kamenik, Anna S, Hofer, Florian, Liedl, Klaus R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451023/
https://www.ncbi.nlm.nih.gov/pubmed/32719844
http://dx.doi.org/10.1093/protein/gzaa014