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Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes
Antibodies have the ability to bind various types of antigens and to recognize different antibody-binding sites (epitopes) of the same antigen with different binding affinities. Due to the conserved structural framework of antibodies, their specificity to antigens is mainly determined by their antig...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451023/ https://www.ncbi.nlm.nih.gov/pubmed/32719844 http://dx.doi.org/10.1093/protein/gzaa014 |