Cargando…

A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging

A multifunctional biodegradable brush polymer-drug conjugate (BPDC) is developed for the co-delivery of hydrophobic paclitaxel (PTX) and hydrophilic gemcitabine (GEM) chemotherapeutics, as well as a tumor imaging agent. A novel ternary copolymer of conventional, acetylenyl-functionalized and allyl-f...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Haotian, Yan, Lingyue, Chang, Michael Yu Zarng, Carter, Kevin A., Zhang, Runsheng, Slyker, Leigh, Lovell, Jonathan F., Wu, Yun, Cheng, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451085/
https://www.ncbi.nlm.nih.gov/pubmed/32864564
http://dx.doi.org/10.1039/c9na00282k