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A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging
A multifunctional biodegradable brush polymer-drug conjugate (BPDC) is developed for the co-delivery of hydrophobic paclitaxel (PTX) and hydrophilic gemcitabine (GEM) chemotherapeutics, as well as a tumor imaging agent. A novel ternary copolymer of conventional, acetylenyl-functionalized and allyl-f...
Autores principales: | Sun, Haotian, Yan, Lingyue, Chang, Michael Yu Zarng, Carter, Kevin A., Zhang, Runsheng, Slyker, Leigh, Lovell, Jonathan F., Wu, Yun, Cheng, Chong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451085/ https://www.ncbi.nlm.nih.gov/pubmed/32864564 http://dx.doi.org/10.1039/c9na00282k |
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