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Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II)

INTRODUCTION: Antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment. Over the past 20 years, a number of new drugs have been approved for National Health Service (NHS) use on the basis of information from short-term trials that demonstrate efficacy. These trials do not provide informatio...

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Detalles Bibliográficos
Autores principales: Balabanova, Silviya, Taylor, Claire, Sills, Graeme, Burnside, Girvan, Plumpton, Catrin, Smith, Phil E M, Appleton, Richard, Leach, John Paul, Johnson, Michael, Baker, Gus, Pirmohamed, Munir, Hughes, Dyfrig A, Williamson, Paula R, Tudur-Smith, Catrin, Marson, Anthony Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451282/
https://www.ncbi.nlm.nih.gov/pubmed/32847927
http://dx.doi.org/10.1136/bmjopen-2020-040635