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Modeling of paclitaxel biosynthesis elicitation in Corylus avellana cell culture using adaptive neuro-fuzzy inference system-genetic algorithm (ANFIS-GA) and multiple regression methods

Paclitaxel as a microtubule-stabilizing agent is widely used for the treatment of a vast range of cancers. Corylus avellana cell suspension culture (CSC) is a promising strategy for paclitaxel production. Elicitation of paclitaxel biosynthesis pathway is a key approach for improving its production i...

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Detalles Bibliográficos
Autores principales: Farhadi, Siamak, Salehi, Mina, Moieni, Ahmad, Safaie, Naser, Sabet, Mohammad Sadegh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451515/
https://www.ncbi.nlm.nih.gov/pubmed/32853208
http://dx.doi.org/10.1371/journal.pone.0237478