Inhibition of circulating dipeptidyl-peptidase 3 restores cardiac function in a sepsis-induced model in rats: A proof of concept study

Sepsis is a global economic and health burden. Dipeptidyl peptidase 3 (DPP3) is elevated in the plasma of septic patients. The highest levels of circulating DPP3 (cDPP3) are found in non-survivor septic shock patients. The aim of this study was to evaluate the benefits of inhibiting cDPP3 by a speci...

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Detalles Bibliográficos
Autores principales: Deniau, Benjamin, Blet, Alice, Santos, Karine, Vaittinada Ayar, Prabakar, Genest, Magali, Kästorf, Mandy, Sadoune, Malha, de Sousa Jorge, Andreia, Samuel, Jane Lise, Vodovar, Nicolas, Bergmann, Andreas, Mebazaa, Alexandre, Azibani, Feriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451654/
https://www.ncbi.nlm.nih.gov/pubmed/32853284
http://dx.doi.org/10.1371/journal.pone.0238039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451654/
https://www.ncbi.nlm.nih.gov/pubmed/32853284
http://dx.doi.org/10.1371/journal.pone.0238039

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