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Drug screening model meets cancer organoid technology

Tumor organoids inherit the genomic and molecular characteristics of the donor tumor, which not only bridge the gap between genome and phenotype but also circumvent the disadvantages such as genetic information change by using 2D cell lines and the mouse-specific tumor evolution in patient-derived x...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Qin, Tianyu, Huang, Yuhan, Li, Yuan, Chen, Gang, Sun, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451679/
https://www.ncbi.nlm.nih.gov/pubmed/32822897
http://dx.doi.org/10.1016/j.tranon.2020.100840