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Searching for the real function of mTOR signaling in the regulation of PD-L1 expression

The mammalian target of rapamycin (mTOR), via forming two important complexes: mTOR complex 1 (mTORC1) and complex 2 (mTORC2), plays an important role in the regulation of immunity in addition to exerting many other biological funcions. Beyond its regulatory effects on immune cells, the mTOR axis al...

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Detalles Bibliográficos
Autor principal: Sun, Shi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451686/
https://www.ncbi.nlm.nih.gov/pubmed/32854033
http://dx.doi.org/10.1016/j.tranon.2020.100847