Statistical considerations on implementing the MCP-Mod method for binary endpoints in clinical trials

The Multiple Comparison Procedure – Modelling (MCP-Mod) method was qaulified by regulatory agencies (e.g., EMA in 2014 and FDA in 2016) as an efficient statistical method for Phase 2 dose-finding studies when there is uncertainty about dose-response relationship. As this is a relatively new approach...

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Detalles Bibliográficos
Autores principales: Chen, Jingjing, Liu, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451792/
https://www.ncbi.nlm.nih.gov/pubmed/32875139
http://dx.doi.org/10.1016/j.conctc.2020.100641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451792/
https://www.ncbi.nlm.nih.gov/pubmed/32875139
http://dx.doi.org/10.1016/j.conctc.2020.100641

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