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Efficient drug and gene delivery to liver fibrosis: rationale, recent advances, and perspectives

Liver fibrosis results from chronic damages together with an accumulation of extracellular matrix, and no specific medical therapy is approved for that until now. Due to liver metabolic capacity for drugs, the fragility of drugs, and the presence of insurmountable physiological obstacles in the way...

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Detalles Bibliográficos
Autores principales: Mahdinloo, Somayeh, Kiaie, Seyed Hossein, Amiri, Ala, Hemmati, Salar, Valizadeh, Hadi, Zakeri-Milani, Parvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451940/
https://www.ncbi.nlm.nih.gov/pubmed/32874828
http://dx.doi.org/10.1016/j.apsb.2020.03.007