Deconvolving the contributions of cell-type heterogeneity on cortical gene expression

Complexity of cell-type composition has created much skepticism surrounding the interpretation of bulk tissue transcriptomic studies. Recent studies have shown that deconvolution algorithms can be applied to computationally estimate cell-type proportions from gene expression data of bulk blood sampl...

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Detalles Bibliográficos
Autores principales: Patrick, Ellis, Taga, Mariko, Ergun, Ayla, Ng, Bernard, Casazza, William, Cimpean, Maria, Yung, Christina, Schneider, Julie A., Bennett, David A., Gaiteri, Chris, De Jager, Philip L., Bradshaw, Elizabeth M., Mostafavi, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451979/
https://www.ncbi.nlm.nih.gov/pubmed/32804935
http://dx.doi.org/10.1371/journal.pcbi.1008120

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