Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping

Pleiotropy—when a single mutation affects multiple traits—is a controversial topic with far-reaching implications. Pleiotropy plays a central role in debates about how complex traits evolve and whether biological systems are modular or are organized such that every gene has the potential to affect m...

Descripción completa

Detalles Bibliográficos
Autores principales: Geiler-Samerotte, Kerry A., Li, Shuang, Lazaris, Charalampos, Taylor, Austin, Ziv, Naomi, Ramjeawan, Chelsea, Paaby, Annalise B., Siegal, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451985/
https://www.ncbi.nlm.nih.gov/pubmed/32804946
http://dx.doi.org/10.1371/journal.pbio.3000836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451985/
https://www.ncbi.nlm.nih.gov/pubmed/32804946
http://dx.doi.org/10.1371/journal.pbio.3000836

Ejemplares similares