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Systematic identification of functional SNPs interrupting 3’UTR polyadenylation signals

Alternative polyadenylation (APA) is emerging as a widespread regulatory layer since the majority of human protein-coding genes contain several polyadenylation (p(A)) sites in their 3’UTRs. By generating isoforms with different 3’UTR length, APA potentially affects mRNA stability, translation effici...

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Detalles Bibliográficos
Autores principales:	Shulman, Eldad David, Elkon, Ran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451987/ https://www.ncbi.nlm.nih.gov/pubmed/32804959 http://dx.doi.org/10.1371/journal.pgen.1008977

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