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Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis

The killer immunoglobulin-like receptors (KIRs), found predominantly on the surface of natural killer (NK) cells and some T-cells, are a collection of highly polymorphic activating and inhibitory receptors with variable specificity for class I human leukocyte antigen (HLA) ligands. Fifteen KIR genes...

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Detalles Bibliográficos
Autores principales: Hanson, Aimee L., Vukcevic, Damjan, Leslie, Stephen, Harris, Jessica, Lê Cao, Kim-Anh, Kenna, Tony J., Brown, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451988/
https://www.ncbi.nlm.nih.gov/pubmed/32804949
http://dx.doi.org/10.1371/journal.pgen.1008906