Cytosolic ME1 integrated with mitochondrial IDH2 supports tumor growth and metastasis

NADPH is a pivotal cofactor that maintains redox homeostasis and lipogenesis in cancer cells and interference with NADPH production is a promising approach for treating cancer. However, how normal and cancer cells differentially exploit NADPH-producing pathways is unclear, and selective approaches t...

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Detalles Bibliográficos
Autores principales: Shao, Chang, Lu, Wenjie, Du, Ye, Yan, Wenchao, Bao, Qiuyu, Tian, Yang, Wang, Guangji, Ye, Hui, Hao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452056/
https://www.ncbi.nlm.nih.gov/pubmed/32853879
http://dx.doi.org/10.1016/j.redox.2020.101685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452056/
https://www.ncbi.nlm.nih.gov/pubmed/32853879
http://dx.doi.org/10.1016/j.redox.2020.101685

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