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Oxidation of HDAC4 by Nox4-derived H(2)O(2) maintains tube formation by endothelial cells

NADPH oxidases produce reactive oxygen species that differ in localization, type and concentration. Within the Nox family only Nox4 produces H(2)O(2) which can directly oxidize cysteine residues. With this post-translational modification, activity, stability, localization and protein-protein interac...

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Detalles Bibliográficos
Autores principales: Schader, Tim, Löwe, Oliver, Reschke, Christina, Malacarne, Pedro, Hahner, Fabian, Müller, Niklas, Gajos-Draus, Anna, Backs, Johannes, Schröder, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452117/
https://www.ncbi.nlm.nih.gov/pubmed/32818796
http://dx.doi.org/10.1016/j.redox.2020.101669