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Oxidation of HDAC4 by Nox4-derived H(2)O(2) maintains tube formation by endothelial cells
NADPH oxidases produce reactive oxygen species that differ in localization, type and concentration. Within the Nox family only Nox4 produces H(2)O(2) which can directly oxidize cysteine residues. With this post-translational modification, activity, stability, localization and protein-protein interac...
Autores principales: | Schader, Tim, Löwe, Oliver, Reschke, Christina, Malacarne, Pedro, Hahner, Fabian, Müller, Niklas, Gajos-Draus, Anna, Backs, Johannes, Schröder, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452117/ https://www.ncbi.nlm.nih.gov/pubmed/32818796 http://dx.doi.org/10.1016/j.redox.2020.101669 |
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