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Modified mRNA-LNP Vaccines Confer Protection against Experimental DENV-2 Infection in Mice
Dengue virus (DENV) infection is a major global public health concern, and there is no effective vaccine for it. In this study, we describe the design and characterization of three nucleotide-modified mRNA vaccines (prME-mRNA, E80-mRNA, and NS1-mRNA) for DENV-2. Our results showed that vaccination w...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452130/ https://www.ncbi.nlm.nih.gov/pubmed/32913878 http://dx.doi.org/10.1016/j.omtm.2020.07.013 |