USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea

Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deliverable siRNAs [sdRNAs]) are a novel modality for...

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Detalles Bibliográficos
Autores principales: Boumil, Edward F., Castro, Nileyma, Phillips, Andrew T., Chatterton, Jon E., McCauley, Sean M., Wolfson, Alexey D., Shmushkovich, Taisia, Ridilla, Marc, Bernstein, Audrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452140/
https://www.ncbi.nlm.nih.gov/pubmed/32829179
http://dx.doi.org/10.1016/j.omtn.2020.07.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452140/
https://www.ncbi.nlm.nih.gov/pubmed/32829179
http://dx.doi.org/10.1016/j.omtn.2020.07.032

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