Cargando…

USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea

Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deliverable siRNAs [sdRNAs]) are a novel modality for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boumil, Edward F., Castro, Nileyma, Phillips, Andrew T., Chatterton, Jon E., McCauley, Sean M., Wolfson, Alexey D., Shmushkovich, Taisia, Ridilla, Marc, Bernstein, Audrey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452140/ https://www.ncbi.nlm.nih.gov/pubmed/32829179 http://dx.doi.org/10.1016/j.omtn.2020.07.032

Ejemplares similares

Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs
por: Shmushkovich, Taisia, et al.
Publicado: (2018)

USP10 Promotes Fibronectin Recycling, Secretion, and Organization
por: Phillips, Andrew T., et al.
Publicado: (2021)

Scars and Opacities of the Cornea and Their Treatment
por: Guha, G. S.
Publicado: (1941)

Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
por: Berezhnoy, Alexey, et al.
Publicado: (2012)

Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma
por: Ligtenberg, Maarten A., et al.
Publicado: (2018)

Deliverance
por: Dickey, James
Publicado: (1970)

Manipulation of Panx1 Activity Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells
por: Basova, Liana V., et al.
Publicado: (2017)

Topical Rosiglitazone Is an Effective Anti-Scarring Agent in the Cornea
por: Huxlin, Krystel R., et al.
Publicado: (2013)

Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs
por: Lu, Yi, et al.
Publicado: (2018)

The Deliverances of the Retina
por: Blackham, Geo. E.
Publicado: (1882)

The Deliverances of the Retina
por: Abbott, F. W.
Publicado: (1882)

Direct Delivery of Apatite Nanoparticle-Encapsulated siRNA Targeting TIMP-1 for Intractable Abnormal Scars
por: Aoki, Masayo, et al.
Publicado: (2020)

Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery
por: Chun, Yong Yao, et al.
Publicado: (2021)

Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA
por: Yingyuad, Peerada, et al.
Publicado: (2014)

Where should siRNAs go: applicable organs for siRNA drugs
por: Ahn, Insook, et al.
Publicado: (2023)

RF multipoles deliverable
por: Cruz Alaniz, Emilia, et al.
Publicado: (2020)

Fabian Deliverances on Sanatoria
Publicado: (1913)

Targeted therapy for cisplatin‐resistant lung cancer via aptamer‐guided nano‐zinc carriers containing USP14 siRNA
por: Zhao, Xinmin, et al.
Publicado: (2023)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

siRNA for Influenza Therapy
por: Barik, Sailen
Publicado: (2010)

Retrovirus-delivered siRNA
por: Devroe, Eric, et al.
Publicado: (2002)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Genome-wide screens for effective siRNAs through assessing the size of siRNA effects
por: Zhang, Xiaohua Douglas
Publicado: (2008)

Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities
por: Ichihara, Masatoshi, et al.
Publicado: (2007)

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
por: Ballarín-González, Borja, et al.
Publicado: (2013)

sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
por: Shah, Jyoti K, et al.
Publicado: (2007)

Expression data of HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the presence of BubR1 siRNA
por: Nakayama, Yusuke, et al.
Publicado: (2015)

Correction to: Targeted therapy for cisplatin‐resistant lung cancer via aptamer‐guided nano‐zinc carriers containing USP14 siRNA
por: Zhao, Xinmin, et al.
Publicado: (2023)

An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses
por: Cheng, Norton, et al.
Publicado: (2023)

Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury
por: Woller, Sarah A., et al.
Publicado: (2022)

Control of Scar Tissue Formation in the Cornea: Strategies in Clinical and Corneal Tissue Engineering
por: Wilson, Samantha L., et al.
Publicado: (2012)

siRNAdb: a database of siRNA sequences
por: Chalk, Alistair M., et al.
Publicado: (2005)

siRNAdb: a database of siRNA sequences
por: Chalk, Alistair M., et al.
Publicado: (2005)

CASE method: tasks and deliverables
por: Barker, Richard
Publicado: (1990)

Finding deliverance from Coronavirus
por: Gupta, Harish, et al.
Publicado: (2022)

Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles
por: Kummitha, China M, et al.
Publicado: (2012)

Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates
por: Foster, Donald J., et al.
Publicado: (2018)

Predicting siRNA efficacy based on multiple selective siRNA representations and their combination at score level
por: He, Fei, et al.
Publicado: (2017)

Computational models with thermodynamic and composition features improve siRNA design
por: Shabalina, Svetlana A, et al.
Publicado: (2006)

Aptamer mediated siRNA delivery
por: Chu, Ted C., et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_gv7onnnaadegjhld98uspuj3in