STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5

Loss of midbrain dopaminergic (mDA) neurons and their axons is central to Parkinson's disease (PD). Growth differentiation factor (GDF)5 is a potential neurotrophic factor for PD therapy. However, the molecular mediators of its neurotrophic action are unknown. Our proteomics analysis shows that...

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Detalles Bibliográficos
Autores principales: Anantha, Jayanth, Goulding, Susan R., Wyatt, Sean L., Concannon, Ruth M., Collins, Louise M., Sullivan, Aideen M., O'Keeffe, Gerard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452236/
https://www.ncbi.nlm.nih.gov/pubmed/32853992
http://dx.doi.org/10.1016/j.isci.2020.101457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452236/
https://www.ncbi.nlm.nih.gov/pubmed/32853992
http://dx.doi.org/10.1016/j.isci.2020.101457

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